The “switch” that regulates the use of fat

Researchers have found in laboratory models the mechanisms by which “white fats” are transformed into “brown fats”. Fat in the body is stored in specialized cells called adipocytes. Which can change from one state to another and back again. White fats, as we know, are those that “save” energy, while brown fats use it.** The study published in Cell Metabolism Today shows that after eating the brain responds by increasing insulin levels, after an increase in blood glucose. The brain then sends signals to transform the fat into brown fat for energy. In contrast, after fasting, the brain instructs these adipocytes to become targets for energy storage again. These processes help prevent excess weight loss in response to eating. Which means that body weight remains relatively stable. The researchers showed that the brain’s function in sensing insulin and coordinating energy expenditure is controlled by a mechanism similar to the switch activated after fasting to inhibit the insulin response, repress brown adipocytes, and conserve energy. As well as turn off after eating to facilitate the response to insulin and promote the transformation of adipocytes into brown ones to expend energy. This means that there is a fundamental mechanism that normally ensures that energy use is on par with energy intake. When this doesn’t work correctly is when our patients (and we) gain (gain) weight. Researchers are now investigating the possibility of inhibiting this “switch” for therapeutic purposes. And try to promote the loss of excess fat.  Although they also affirm that any therapeutic use** is still something in the future.** You can read the entire research here: http://www.cell.com/cell-metabolism/fulltext/S1550-4131(17)30434-5